Aranciamycin
Aranciamycin (Compound 1) is an anthracycline antibiotic with collagenase inhibitory activity (IC503.7*10-7M). Aranciamycin can be used to inhibit DNA synthesis in tumor cells .
For research use only. We do not sell to patients.
- CAS No.: 72389-06-1
- Formula: C27H28O12
- Molecular Weight:544.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
2.7 μM
Compound: 7
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Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
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[PMID: 38412432] |
| HeLa | IC50 |
2.7 μM
Compound: 3
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Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST8 assay
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[PMID: 20192240] |
| HepG2 | IC50 |
18 μM
Compound: 4
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Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
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[PMID: 25789410] |
| HL-60 | IC50 |
4.1 μM
Compound: 3
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Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST8 assay
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[PMID: 20192240] |
| KB 3-1 | IC50 |
>30 μM
Compound: 4
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Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human KB-3-1 cells assessed as growth inhibition after 48 hrs by MTT assay
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[PMID: 25789410] |
| NCI-H460 | IC50 |
>30 μM
Compound: 4
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Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as growth inhibition after 48 hrs by MTT assay
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[PMID: 25789410] |
| PC-3 | IC50 |
1.1 μM
Compound: 7
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Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by alamar blue assay
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[PMID: 38412432] |
| SW-620 | IC50 |
>30 μM
Compound: 4
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Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human SW620 cells assessed as growth inhibition after 48 hrs by MTT assay
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[PMID: 25789410] |
Chemical Information
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CAS No. 72389-06-1
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Molecular Weight 544.50
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Formula C27H28O12
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SMILES
O=C1[C@@](C)(O)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)OC)C(C(O)=C3C(C4=C5C=CC=C4O)=O)=C1C=C3C5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aranciamycin Related Classifications
HY-123886 Related Classifications
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