1. Anti-infection
  2. Antibiotic
    Bacterial
  3. Indolmycin

Indolmycin (Synonyms: TAK-083; PA-155A)

Cat. No.: HY-117319
Handling Instructions

Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity.

For research use only. We do not sell to patients.

Indolmycin Chemical Structure

Indolmycin Chemical Structure

CAS No. : 21200-24-8

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Description

Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA ligase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3].

In Vitro

Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas a single strain exhibited high-level resistance (MIC 128 mg/L)[2].

Molecular Weight

257.29

Formula

C₁₄H₁₅N₃O₂

CAS No.

21200-24-8

SMILES

O=C1N=C(NC)O[[email protected]]1[[email protected]@H](C2=CNC3=C2C=CC=C3)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

IndolmycinTAK-083PA-155ATAK083TAK 083AntibioticBacterialInhibitorinhibitorinhibit

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