21200-24-8
21200-24-8
Chemical Structure
Indolmycin
Synonym(s): TAK-083; PA-155A
- CAS No.: 21200-24-8
- Formula:C14H15N3O2
- Molecular Weight:257.29
IUPAC Name: (S)-5-((R)-1-(1H-indol-3-yl)ethyl)-2-(methylamino)oxazol-4(5H)-one
InChIKey: GNTVWGDQPXCYBV-PELKAZGASA-N
SMILES: O=C1N=C(NC)O[C@H]1[C@@H](C2=CNC3=C2C=CC=C3)C
Biological Activity: Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indolmycin | 99% | Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.59
HY-W782635DL-5-Indolylmethylhydantoin -
Similarity Score 0.59
HY-121954Necrostatin-1 (inactive control) -
Similarity Score 0.59
HY-15760Necrostatin-1 -
Similarity Score 0.58
HY-P2092Cyclo(L-leucyl-L-tryptophyl) -
Similarity Score 0.58
HY-N1436L-(+)-Abrine -
Similarity Score 0.58
HY-W923640N-Methyl-DL-tryptophan -
Similarity Score 0.57
HY-W008766L-Tryptophanamide hydrochloride -
Similarity Score 0.57
HY-W343816D,L-Tryptophanamide hydrochloride -
Similarity Score 0.57
HY-184077IDO1-IN-35 -
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References
- [1]. R G Werner, et al. Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligase. Eur J Biochem. 1976 Sep;68(1):1-3. [Content Brief]
- [2]. Julian G Hurdle, et al. Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections. J Antimicrob Chemother. 2004 Aug;54(2):549-52. [Content Brief]
- [3]. M R Harnden, et al. Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. J Med Chem. 1978 Jan;21(1):82-7. [Content Brief]
