IDO1-IN-35
IDO1-IN-35 is an inhibitor of the IDO1 mutant IDO1F164A. IDO1-IN-35 inhibits the IDO1-mediated conversion of L-tryptophan to N-formyl-L-kynurenine. IDO1-IN-35 can be used in studies of viral and bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 2701898-79-3
- Formula: C12H13ClN2O2
- Molecular Weight:252.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
IDO1 |
In Vitro
IDO1-IN-35 (compound 16) (100 μM-1 mM; 15 min pre-incubation) inhibits recombinant human IDO1F164A-mediated L-tryptophan metabolism at 1 mM but shows no inhibition at 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 2701898-79-3
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Molecular Weight 252.70
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Formula C12H13ClN2O2
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SMILES
O=C(C1(CC1C2=CNC3=C2C=CC=C3)N)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1-IN-35 Related Classifications
HY-184077 Related Classifications
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