Oxytetracycline calcium
Based on 10 publication(s) in Google Scholar
Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity.
For research use only. We do not sell to patients.
- CAS No.: 7179-50-2
- Formula: C22H24CaN2O9
- Molecular Weight:500.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Oxytetracycline calcium
More- Theranostics. 2022 Jan 1;12(3):1187-1203. [Abstract]
- Water Res. 2023 Jul 15:240:120110. [Abstract]
- Food Chem X. 2026 Feb 8:34:103646. [Abstract]
- J Hazard Mater Adv. 2025 Nov 12;20:100939.
- ACS Omega. 2025 Sep 10;10(37):42791-42805. [Abstract]
- Sci Rep. 2022 Aug 25;12(1):14502. [Abstract]
- Saudi Pharm J. 2021 Jun;29(6):566-575. [Abstract]
- Water. 2025 Jun 6.
- SSRN. 2025 Dec 31.
- Chemosphere. 2019 Jun:225:378-387. [Abstract]
All Antibiotic Isoforms
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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HSV-1 |
Tetracycline |
Human Endogenous Metabolite |
Microbial Metabolite |
Oxytetracycline calcium is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. Oxytetracycline calcium is synthesized by a type II polyketide synthase that generates the poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications by cyclases, oxygenases, transferases, and additional tailoring enzymes[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
For Oxytetracycline calcium, the limits are 100 μg/kg in muscle and milk, 200 μg/kg in egg, 300 μg/kg in liver and 600 μg/kg in kidney. Oxytetracycline calcium is administered to fish as medicated feed at concentrations ranging from 35 to 75 mg a.i kg-1 biomass day-1 for 7-14 days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7179-50-2
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Molecular Weight 500.51
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Formula C22H24CaN2O9
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SMILES
O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N.[Ca]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (10)
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Journal Impact Factor
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Most Recent
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Theranostics
Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents. [Abstract]2022 Jan 1;12(3):1187-1203. PMID: 35154482 -
Water Res
Quantifying community-wide antibiotic usage via urban water fingerprinting: Focus on contrasting resource settings in South Africa. [Abstract]2023 Jul 15:240:120110. PMID: 37247434 -
Food Chem X
Machine learning prioritization of antibiotic residues in aquatic foods reveals exposure-driven genotoxic risk mediated by BCL2. [Abstract]2026 Feb 8:34:103646. PMID: 41756597 -
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ACS Omega
Solvothermal Synthesis of Functionalized UiO-66/Fe3O4@CNCs for Selective Removal of Oxytetracycline. [Abstract]2025 Sep 10;10(37):42791-42805. PMID: 41018641 -
Sci Rep
Qualitative immunoassay for the determination of tetracycline antibiotic residues in milk samples followed by a quantitative improved HPLC-DAD method. [Abstract]2022 Aug 25;12(1):14502. PMID: 36008564 -
Saudi Pharm J
Determination of tetracycline, oxytetracycline and chlortetracycline residues in seafood products of Saudi Arabia using high performance liquid chromatography-Photo diode array detection. [Abstract]2021 Jun;29(6):566-575. PMID: 34194263 -
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Chemosphere
Mass-balance-model-based evaluation of sewage treatment plant contribution to residual pharmaceuticals in environmental waters. [Abstract]2019 Jun:225:378-387. PMID: 30884299
Purity & Documentation
References
[1]. Elia, A.C., et al., Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem, 2014. [Content Brief]
[2]. Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Oxytetracycline calcium Related Classifications
HY-B0275C Related Classifications
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