Mycaminosyltylonolide 

Mycaminosyltylonolide is a potent antibiotic. Mycaminosyltylonolide shows antibacterial activity. Mycaminosyltylonolide inhibits luciferase synthesis^[1][2].

Mycaminosyltylonolid (3 µM) inhibits firefly luciferase mRNA translation in E. coli S30^[1].
Mycaminosyltylonolid (0-128 µg/mL) shows antibacterial activity with MIC values of 1, 1, 2, 2, 1, 64 µg/mL for S. aureus FDA209Pa, S. aureus Smitha, S. aureus KUB857c, S. epidermidis KUB795g, E. faecalis ATCC29212h, K. pneumoniae NCTC9632h, respectively^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

597.74

C₃₁H₅₁NO₁₀

61257-02-1

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Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Shishkina A, et al. Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. Bioconjug Chem. 2013 Nov 20;24(11):1861-9.  [Content Brief]

  [2]. Sugawara A, et al. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity. J Antibiot (Tokyo). 2017 Jul;70(8):878-887.  [Content Brief]