2. Anti-infection
  3. Antibiotic Bacterial
  4. Cefpodoxime

Cefpodoxime  (Synonyms: Cefpodoxime acid; R 3763)

Cat. No.: HY-A0251 Purity: 98.75%
COA Handling Instructions

Molarity Calculator

Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research.

For research use only. We do not sell to patients.

Cefpodoxime Chemical Structure

Cefpodoxime Chemical Structure

CAS No. : 80210-62-4

Size Price Stock Quantity
5 mg USD 65 In-stock
10 mg USD 105 In-stock
25 mg USD 220 In-stock
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Based on 1 publication(s) in Google Scholar

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Cefpodoxime Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Cefpodoxime (Cefpodoxime acid) is a potent antibiotic active against gram-positive and gram-negative bacteria. Cefpodoxime inhibits the majority of cells in microbial populations. Cefpodoxime can be used for acute otitis media, sinusitis and tosillopharyngitis research[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cefpodoxime (Cefpodoxime acid) inhibits gram-negative anaerobic rods (Bacteroidaceae) with MIC values of 0.125-4 mg/L. Cefpodoxime inhibits Veillonella parvula with MIC values of 0.25-8 mg/L. Cefpodoxime inhibits Peptostreptococcus micros, Peptostreptococcus asaccharolyticus and Ruminococcus bromii with MIC values of <2 mg/L[1].
Cefpodoxime (Cefpodoxime acid) inhibits bacterial populations of S. pneumoniae and S. pyogenes. cfu[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cefpodoxime Related Antibodies
In Vivo

Cephalosporins (2.5-50 mg/kg; p.o.; every 8 hours; for 48 hours) have good curative effect in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Swiss CD1 mice[3]
Dosage: 2.5, 5, 10, 25, 40 and 50 mg/kg
Administration: Oral administration; every 8 hours; for 48 hours
Result: Efficacy was obtained with values of >350.
Clinical Trial
Molecular Weight

427.46

Formula

C15H17N5O6S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N12)=C(COC)CS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (584.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3394 mL 11.6970 mL 23.3940 mL
5 mM 0.4679 mL 2.3394 mL 4.6788 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.75%

COA (255 KB) HNMR (281 KB) LCMS (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3394 mL 11.6970 mL 23.3940 mL 58.4850 mL
5 mM 0.4679 mL 2.3394 mL 4.6788 mL 11.6970 mL
10 mM 0.2339 mL 1.1697 mL 2.3394 mL 5.8485 mL
15 mM 0.1560 mL 0.7798 mL 1.5596 mL 3.8990 mL
20 mM 0.1170 mL 0.5849 mL 1.1697 mL 2.9243 mL
25 mM 0.0936 mL 0.4679 mL 0.9358 mL 2.3394 mL
30 mM 0.0780 mL 0.3899 mL 0.7798 mL 1.9495 mL
40 mM 0.0585 mL 0.2924 mL 0.5849 mL 1.4621 mL
50 mM 0.0468 mL 0.2339 mL 0.4679 mL 1.1697 mL
60 mM 0.0390 mL 0.1950 mL 0.3899 mL 0.9748 mL
80 mM 0.0292 mL 0.1462 mL 0.2924 mL 0.7311 mL
100 mM 0.0234 mL 0.1170 mL 0.2339 mL 0.5849 mL
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Cefpodoxime Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefpodoxime80210-62-4Cefpodoxime acid R 3763R3763R 3763R-3763AntibioticBacterialgram-positive bacteriagram-negative bacteriabacterialantibioticInhibitorinhibitorinhibit

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