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L-Alanosine (Synonyms: NSC-153353)

Cat. No.: HY-16933 Purity: >99.0%
Handling Instructions

L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency.

For research use only. We do not sell to patients.

L-Alanosine Chemical Structure

L-Alanosine Chemical Structure

CAS No. : 5854-93-3

Size Price Stock Quantity
1 mg USD 70 In-stock
Estimated Time of Arrival: December 31
5 mg USD 210 In-stock
Estimated Time of Arrival: December 31
10 mg USD 360 Get quote
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

L-Alanosine (NSC-153353), an antibiotic from Streptomyces alanosinicus, has antineoplastic activity. L-Alanosine (NSC-153353) inhibits adenylosuccinate synthetase, which converts inosine monophospate (IMP) into adenylosuccinate. L-Alanosine (NSC-153353) blocks the common de novo purine biosynthesis pathway and, thereby, inhibits tumor cells with MTAP deficiency[1][2][3].

Molecular Weight

149.11

Formula

C₃H₇N₃O₄

CAS No.

5854-93-3

SMILES

N[[email protected]@H](CN(O)N=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 15 mg/mL (100.60 mM; ultrasonic and adjust pH to 8 with 水)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.7065 mL 33.5323 mL 67.0646 mL
5 mM 1.3413 mL 6.7065 mL 13.4129 mL
10 mM 0.6706 mL 3.3532 mL 6.7065 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: >99.0%

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L-Alanosine
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HY-16933
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