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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

PEG conjugate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) ADC Linker (431) ADC Payload (4) Akt (1) Amino Acid Derivatives (1) Amyloid-β (1) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (1) Antibiotic (4) Antibody-Drug Conjugates (ADCs) (4) Apoptosis (73) Aurora Kinase (1) AUTACs (4) Autophagy (69) AUTOTACs (3) Bacterial (1) Beta-lactamase (1) Biochemical Assay Reagents (294) Btk (2) c-Kit (1) c-Met/HGFR (3) Casein Kinase (1) Caspase (1) CCR (1) CD1 (1) Complement System (1) DNA Alkylator/Crosslinker (2) Drug Derivative (5) Drug Intermediate (6) Drug Isomer (1) Drug-Linker Conjugates for ADC (116) E3 Ligase Ligand-Linker Conjugates (225) EGFR (3) Epigenetic Reader Domain (5) ERK (1) Estrogen Receptor/ERR (2) Ferroptosis (3) FKBP (1) Fluorescent Dye (16) Folate Receptor (FR) (1) Formyl Peptide Receptor (FPR) (1) Glutathione Peroxidase (3) HIV (1) HSP (1) HyT (1) Influenza Virus (1) Integrin (2) JAK (1) LDLR (1) Ligands for Target Protein for PROTAC (1) Liposome (66) Microtubule/Tubulin (21) Mixed Lineage Kinase (1) MMP (1) N-myristoyltransferase (1) nAChR (2) p62 (1) PD-1/PD-L1 (1) Peptide-Drug Conjugates (PDCs) (1) PROTAC Linkers (167) PROTAC-Linker Conjugates for PAC (3) PROTACs (6) PSMA (1) Radionuclide-Drug Conjugates (RDCs) (10) Reactive Oxygen Species (ROS) (1) Reference Standards (13) ROS Kinase (1) SGK (1) Small Interfering RNA (siRNA) (1) SNIPERs (1) STING (3) Target Protein Ligand-Linker Conjugates (9) TNF Receptor (1) Topoisomerase (29)
By Research Areas:	Cancer (820) Cardiovascular Disease (5) Infection (9) Inflammation/Immunology (36) Metabolic Disease (1) Neurological Disease (9)
Click Chemistry:	ADC Synthesis (195) Labeling and Fluorescence Imaging (2) TCO (14) DBCO (62) PROTAC Synthesis (59) BCN (20) Azide (116) Tetrazine (23) Alkynes (64)
Oligonucleotides:	Fluorescent Lipids (11) Pegylated Lipids (72) Aptamers (1) Phospholipids (1) Polymers (4) Cholesterol (1)

1202

Inhibitors & Agonists

Fluorescent Dyes

339

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

295

Click Chemistry

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164239

NH2-PEG3-VC-PAB-MMAE	Drug-Linker Conjugates for ADC Microtubule/Tubulin	Cancer
NH2-PEG3-VC-PAB-MMAE is a *drug-linker conjugate* for ADC*, consisting of a cleavable ADC linker (NH2-PEG3-VC-PAB) and a potent tubulin inhibitor Monomethyl auristatin E (MMAE) (HY-15162). NH2-PEG3-VC-PAB-MMAE* can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-144006

DMPE-PEG2000 ammonium 14:0 PEG2000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium	Liposome	Others
DMPE-PEG2000 ammonium (14:0 PEG2000 PE ammonium) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .

HY-128968

PEG4-aminooxy-MMAF Amberstatin; AS269	Microtubule/Tubulin Drug-Linker Conjugates for ADC	Inflammation/Immunology Cancer
PEG4-aminooxy-MMAF is a *agent-linker conjugate* for ADC** with potent antitumor activity by using the potent antitubulin agent MMAF, linked via the noncleavable PEG4 .

HY-126885

DBCO-PEG5-NHS ester 1 Publications Verification	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W051634

Propargyl-PEG2-amine	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130442

Mal-PEG2-acid	ADC Linker PROTAC Linkers	Cancer
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule . Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W018174

m-PEG3-Amine 1 Publications Verification	ADC Linker PROTAC Linkers	Cancer
m-PEG3-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG3-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130410

Bis-PEG6-NHS ester	ADC Linker PROTAC Linkers	Cancer
Bis-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-136261

DM1-PEG4-DBCO	Drug-Linker Conjugates for ADC	Cancer
DM1-(PEG)4-DBCO is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DM1-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-21930

Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker conjugates 1; E3 Ligase Ligand-Linker conjugates 1	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C-COOH (Cereblon Ligand -Linker Conjugate 1) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-W019793

m-PEG8-NHS ester	ADC Linker	Inflammation/Immunology Cancer
m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-144010

18:1 PEG2000 PE ammonium DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium	Liposome	Others
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .

HY-126976

Propargyl-PEG5-amine	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG5-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG5-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-136133

NHS-PEG2-SS-PEG2-NHS	ADC Linker	Cancer
NHS-PEG2-SS-PEG2-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W190908A

Desthiobiotin-PEG4-NHS ester	Biochemical Assay Reagents	Others
Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-140134

PC Biotin-PEG3-NHS ester	ADC Linker	Cancer
PC Biotin-PEG3-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126958

Biotin-PEG2-acid	PROTAC Linkers ADC Linker	Inflammation/Immunology Cancer
Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Biotin-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-126960

Mal-PEG1-acid	PROTAC Linkers ADC Linker	Inflammation/Immunology Cancer
Mal-PEG1-acid is is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

HY-103599

(S,R,S)-AHPC-PEG2-N3 1 Publications Verification VH032-PEG2-N3; VHL Ligand-Linker conjugates 6; E3 ligase Ligand-Linker conjugates 13	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG2-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-N3 can be used for the synthesis of PROTACs .

HY-118808

Propargyl-PEG2-NHBoc	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W879004

m-PEG16-NHS ester	Biochemical Assay Reagents	Others
m-PEG16-NHS ester is a PEG derivative composed of an NHS ester that can be conjugated to amino acids or other molecules containing amino groups .

HY-130654

(S,R,S)-AHPC-C2-PEG4-N3 VH032-C2-PEG4-N3	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC₅₀) of 82 nM . (S,R,S)-AHPC-C2-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-126893

Bis-PEG8-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W190908C

Desthiobiotin-PEG12-NHS ester	Biochemical Assay Reagents	Others
Desthiobiotin-PEG12-NHS ester is a PEG derivative composed of desthiobiotin, 12 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-W190908B

Desthiobiotin-PEG6-NHS ester	Biochemical Assay Reagents	Others
Desthiobiotin-PEG6-NHS ester is a PEG derivative composed of desthiobiotin, 6 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.

HY-133050

Hydroxy-PEG6-acid	ADC Linker	Cancer
Hydroxy-PEG6-acid is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .

HY-138488

Biotin-PEG4-PFP ester	ADC Linker	Cancer
Biotin-PEG4-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-126892

Bis-PEG7-acid	PROTAC Linkers ADC Linker	Cancer
Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130387

Propargyl-PEG4-Tos	PROTAC Linkers ADC Linker	Cancer
Propargyl-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG4-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140310

TCO-PEG4-DBCO	ADC Linker PROTAC Linkers	Cancer
TCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-126496

PEG4-SPDP	ADC Linker	Cancer
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).

HY-144001

DSPE-PEG-Carboxylic acid ammonium	Liposome	Others
DSPE-PEG-Carboxylic acid ammonium is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes .

HY-144000A

DSPE-PEG2000-PDP	Liposome	Others
DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications .

HY-117050

PEG12-Tos	ADC Linker PROTAC Linkers	Cancer
Tos-PEG12 is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PEG12-Tos is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-160280

DOPE-PEG2000-Fluor 647	Liposome Fluorescent Dye	Others
DOPE-PEG2000-Fluor 647 is a PEG-lipid-dye conjugate. composed of a DOPE phospholipid and a Fluor 647 dye .

HY-136051

Biotin-PEG3-aldehyde	ADC Linker	Cancer
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-120258

Tr-PEG3-OH	ADC Linker	Inflammation/Immunology Cancer
Tr-PEG3-OH is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-172351A

PEG6000-bis-amine	Biochemical Assay Reagents	Cancer
PEG6000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .

HY-172351B

PEG10000-bis-amine	Biochemical Assay Reagents	Cancer
PEG10000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .

HY-P10946

FAP targeting peptide-PEG2 conjugate	Radionuclide-Drug Conjugates (RDCs)	Cancer
FAP targeting peptide-PEG2 conjugate (Example A1) is the peptide (HY-P10945) and linker conjugate of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-174813

Pomalidomide-PEG3-Cys	E3 Ligase Ligand-Linker Conjugates	Others
Pomalidomide-PEG3-Cys is an E3 ligase ligand-linker conjugate that incorporates a CRBN ligand Pomalidomide (HY-10984) and 3-unit PEG linker. Pomalidomide-PEG3-Cys can be used for synthesis of PROTAC BRD4 Degrader-33 (HY-174811) .

HY-172465

DSPE-PEG5000-cRGD	Liposome Integrin	Cardiovascular Disease Cancer
DSPE-PEG5000-cRGD is a PEG conjugate composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. DSPE-PEG5000-cRGD is applicable for research on drug delivery, cancer and vascular diseases .

HY-126894

Bis-PEG9-acid	PROTAC Linkers ADC Linker	Cancer
Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-130408

m-PEG6-Amine 1 Publications Verification	ADC Linker PROTAC Linkers	Cancer
m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-135964

(2-pyridyldithio)-PEG4 acid	ADC Linker	Cancer
(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-138484

Folate-PEG3-amine	ADC Linker	Cancer
Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-133544

Mal-CO-PEG5-NHS ester	ADC Linker	Cancer
Mal-CO-PEG5- NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

HY-136048

Methylcyclopropene-PEG4-NHS	ADC Linker	Cancer
Methylcyclopropene-PEG4-NHS is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-136047

Methylcyclopropene-PEG3-amine	ADC Linker	Cancer
Methylcyclopropene-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-172351

PEG400-bis-amine	Biochemical Assay Reagents	Cancer
PEG400-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .

Cat. No.	Product Name	Type

HY-159194

DSPE-PEG2000-Cy5.5	Fluorescent Dyes
DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .

HY-D2433

Glucose-PEG2000-Cy3	Fluorescent Dyes
Glucose-PEG2000-Cy3 is a Cy3 (HY-D0822) labeled Glucose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Glucose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .

HY-138300GL

ALC-0159 (GMP Like)	Fluorescent Dyes
ALC-0159 (GMP Like) is the GMP Like class ALC-0159 (HY-138300). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-D2438

CDDP-PEG-Cy3

Fluorescent Dyes

CDDP-PEG-Cy3 is a CDDP-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Cisplatin (CDDP) (HY-17394) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .

HY-D2437

DOX-PEG-Cy3	Fluorescent Dyes
DOX-PEG-Cy3 (Doxorubicin-PEG-Cy3) is a Cy3 (HY-D0822) labeled DOX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. DOX is a broad-spectrum anthracycline antibiotic with cytotoxic properties .

HY-D2440

cRGD-PEG-Cy3	Fluorescent Dyes
cRGD-PEG-Cy3 is a Cy3 (HY-D0822) labeled cRGD-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. cRGD can be used to modify lipid for improved stability .

HY-D2436

PTX-PEG-Cy3

Fluorescent Dyes

PTX-PEG-Cy3 (Paclitaxel-PEG-Cy3) is a Cy3 (HY-D0822) labeled PTX-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. PTX stabilizes tubulin polymerization. PTX can cause both mitotic arrest and apoptotic cell death. PTX also induces autophagy .

HY-177414

BB-1701

Fluorescent Dyes

BB-1701 is an anti-HER2 antibody-drug conjugate (ADC). BB-1701 is composed of a humanized anti-HER2 antibody (Trastuzumab) (HY-P9907), a linker (Mal-PEG2-VCP), a microtubule inhibitor (Eribulin) (HY-13442), and the drug-linker conjugate for ADC is Mal-PEG2-VCP-Eribulin (HY-128870). BB-1701 has a potent cytotoxicity and bystander effects on tumors with heterogeneous target expression. BB-1701 significantly induces immunogenic cell death and the activation of the immune .

HY-42972G

DBCO-acid	Fluorescent Dyes
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-D2429

Dextran-PEG-Cy3	Fluorescent Dyes
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .

HY-D2431

Galactose-PEG-Cy3	Fluorescent Dyes
Galactose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Galactose-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Galactose-PEG improves drug cellular uptake and reduces endosomal degradation, and can be used in drug delivery .

HY-D2435

MTX-PEG-Cy3

Fluorescent Dyes

CDDP-PEG-Cy3 is a MTX-PEG conjugate labeled with Cy3 (HY-D0822). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Methotrexate (Amethopterin; MTX) (HY-14519), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) .

HY-D2428

OVA-PEG-Cy3

Fluorescent Dyes

OVA-PEG-Cy3 is a Cy3 (HY-D0822)-labeled OVA-PEG conjugate. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. The maximum emission wavelength of Cy3 is approximately 562-570 nm. Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .

Cat. No.	Product Name	Target	Research Area

HY-P10646

Muscle homing peptide M12	Biochemical Assay Reagents	Neurological Disease
Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction .

HY-P10946

FAP targeting peptide-PEG2 conjugate	Radionuclide-Drug Conjugates (RDCs)	Cancer
FAP targeting peptide-PEG2 conjugate (Example A1) is the peptide (HY-P10945) and linker conjugate of Unlabeled FXX489 (HY-P10944). Unlabeled FXX489 is a fibroblast activation protein (FAP)-targeting ligand .

HY-P10783

BGC0222	Peptide-Drug Conjugates (PDCs) Integrin	Cancer
BGC0222 is a novel prodrug of Irinotecan (HY-16562). BGC0222, as a PEG-cRGD-conjugated Irinotecan (HY-16562) derivative, could slowly and steadily release Irinotecan (HY-16562). BGC0222 binds to α_Vβ₃ with IC₅₀ values of 4.25 μM (α_Vβ₃) and 58.7 μM (α_Vβ₅). BGC0222 possesses the property of inducing neovascularization. BGC0222 exhibits good antiproliferation activity in many tumors .

HY-P11718

cFLFLF	Formyl Peptide Receptor (FPR) Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
cFLFLF is a FPR-specific peptide. cFLFLF is sequentially conjugated with a bifunctional polyethylene glycol moiety (PEG, 3.4 kD) and a DOTA through a lysine (K) spacer and finally labeled with ⁶⁴Cu-CuCl₂ to form cFLFLFKPEG- ⁶⁴Cu. cFLFLFKPEG- ⁶⁴Cu is a neutrophil-specific PET imaging agent .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991930

ARX305 Antibody	ADC Antibody TNF Receptor	Cancer
ARX305 Antibody is an anti-human CD70 antibody. ARX305 Antibody can generate antibody drug conjugate (ADC) (ARX305) with a potent microtubule inhibitor PEG4-aminooxy-MMAF (AS269) (HY-128968). ARX305 Antibody can be used for the study of multiple solid and hematological cancers .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N16321

C18:0 DG-PEG2K-triGalNAc	Lipid	Biochemical Assay Reagents
C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that consists of a C18:0 DG unit conjugated to a triGalNAc. C18:0 DG-PEG2K-triGalNAc can be used to prepare lipid nanoparticles for drug delivery.

HY-N15903

DSPE-PEG2k-tri Mannose ammonium	Lipid	Biochemical Assay Reagents
DSPE-PEG2k-tri Mannose ammonium is a trimannose-DSPE-conjugated PEG derivative that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16285

DSPE-PEG400 carboxylic acid sodium	Lipid	Biochemical Assay Reagents
DSPE-PEG400 carboxylic acid sodium is a lipid that consists of a DSPE-PEG400 unit conjugated to a carboxy group. DSPE-PEG400 carboxylic acid sodium can be used to prepare lipid nanoparticles for drug delivery.

HY-N16234

Chol-PEG1000 fluorescein	Lipid	Fluorescent Dye
Chol-PEG1000 fluorescein is a fluorescent lipid that consists of a cholesterol-PEG1000 unit conjugated to fluorescein. Chol-PEG1000 fluorescein can be used to prepare lipid nanoparticles for drug delivery research (Ex/Em = 480/520 nm).

HY-N16323

DSPE-PEG2K-triGalNAc (II) ammonium	Lipid	Biochemical Assay Reagents
DSPE-PEG2K-triGalNAc (II) ammonium is a functionalized PEG lipid that consists of a DSPE unit conjugated to a triGalNAc. DSPE-PEG2K-triGalNAc (II) ammonium can be used to prepare lipid nanoparticles for drug delivery.

HY-N16299

DSPE-PEG12 carboxy sodium	Lipid	Biochemical Assay Reagents
DSPE-PEG12 carboxy sodium is a lipid that consists of a DSPE-PEG12 unit conjugated to a carboxy group. DSPE-PEG12 carboxy sodium can be used to prepare lipid nanoparticles for drug delivery.

HY-N16233

Chol-PEG2000 fluorescein	Lipid	Fluorescent Dye
Chol-PEG2000 fluorescein is a fluorescent lipid that consists of a cholesterol-PEG2000 unit conjugated to fluorescein. Chol-PEG2000 fluorescein can be used to prepare lipid nanoparticles for drug delivery research (Ex/Em = 480/520 nm).

Cat. No.	Product Name		Classification

HY-138300

ALC-0159 Maximum Cited Publications 15 Publications Verification		Pegylated Lipids
ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-140739

DSPE-PEG2000-Maleimide sodium (purity>95%) 2 Publications Verification		Pegylated Lipids
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .

HY-168374

DSPE-PEG2000-Mannose 1 Publications Verification		Pegylated Lipids
DSPE-PEG 2000-Mannose is a mannose-containing lipid. DSPE-PEG 2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .

HY-147080

Avacincaptad pegol sodium ARC1905		Aptamers
Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system .

HY-144006

DMPE-PEG2000 ammonium 14:0 PEG2000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium		Pegylated Lipids
DMPE-PEG2000 ammonium (14:0 PEG2000 PE ammonium) is a PEG-phospholipid conjugate to prepare nanostructured lipid carrier .

HY-112760

18:0 mPEG2000 PE sodium 1 Publications Verification DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium		Pegylated Lipids
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .

HY-W440823A

DSPE-PEG1000-Amine ammonium DSPE-PEG1000-NH2 ammonium		Pegylated Lipids
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .

HY-W591424

m-PEG2000-NHS ester mPEG2000-SC; mPEG2000-Succinimidyl ester		Polymers
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher *PEG* density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .

HY-W440911

DSPE-PEG2000-Cy5		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-Cy5 is a Cy5 (HY-D0821) fluorophore-labeled conjugate of distearoylphosphatidylethanolamine and polyethylene glycol, as well as a liposome component. The Cy5 fluorophore is commonly used for labeling proteins and nucleic acids in imaging, flow cytometry and genomic applications. DSPE-PEG2000-Cy5 supports cell membrane modification, in vivo tumor targeting research and long-term in vivo circulation of its liposomal formulations (Ex/Em=633/670 nm) .

HY-155882

mPEG750-amine mPEG750-NH2		Polymers
mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-144012

DPPE-PEG2000 ammonium 16:0 PEG2000 PE ammonium; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium		Pegylated Lipids
DPPE-PEG2000 ammonium (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG2000 ammonium enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG2000 ammonium helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG2000 ammonium serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .

HY-172279A

DSPE-PEG2000-TAT		Pegylated Lipids
DSPE-PEG2000-TAT is a cell-penetrating peptide-modified PEGylated phospholipid conjugate and cellular uptake enhancer. DSPE-PEG2000-TAT forms via conjugation of Cys-TAT to DSPE-PEG2000-Mal. DSPE-PEG2000-TAT enhances liposomal cellular uptake and siRNA transfection efficiency in glomerular mesangial and macrophage cells. DSPE-PEG2000-TAT can be used for drug delivery .

HY-144010

18:1 PEG2000 PE ammonium DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium		Pegylated Lipids
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .

HY-144012H

DPPE-PEG5000 16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .

HY-177204

DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW		Pegylated Lipids
DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW is a polypeptide targeting tenascin-X (Tenascin-X) that can be conjugated with liposomes and exosomes. DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW specifically binds to Tenascin-X on the surface of cardiomyocytes, mediates receptor-dependent uptake of nanocarriers, enhances targeted drug delivery of cargo to cardiomyocytes, and increases drug accumulation in cardiac tissue. DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW protects cardiomyocytes treated with LPS, alleviates oxidative stress, repairs mitochondrial function, inhibits ferroptosis and apoptosis, and downregulates the secretion of pro-inflammatory cytokines at the same time. DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW improves cardiac injury and pathological morphology in mice with sepsis-induced cardiomyopathy, restores GPX4 expression, and promotes the internalization of cardiomyocyte-derived exosomes, making it suitable for related research on sepsis-induced cardiomyopathy, myocardial ischemia-reperfusion injury, and other conditions .

HY-144012A

DPPE-PEG350 16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.

HY-W440915

DSPE-PEG2000-FITC		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines .

HY-172705

DSPE-PEG2000-RVG29		Pegylated Lipids
DSPE-PEG2000-RVG29 is a PEG conjugate composed of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB), crosses the BBB, and mediates receptor-dependent transcytosis. DSPE-PEG2000-RVG29 can be used for brain-targeted drug delivery, surface modification of nanocarriers, as well as gene and nucleic acid delivery. DSPE-PEG2000-RVG29 is applicable to research related to hypoxic-ischemic brain injury, Parkinson's disease, and other conditions .

HY-143209B

DSPE-PEG3400		Pegylated Lipids
DSPE-PEG3400 is a phospholipid-PEG polymer conjugate that can be used in drug delivery applications. DSPE-PEG3400 serves as a material for preparing nanocarriers, which is used to prolong blood circulation time, enhance stability and improve encapsulation efficiency .

HY-172699

DSPE-PEG2000-ANG		Pegylated Lipids
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .

HY-W440908

DSPE-PEG2000-Cy3		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-Cy3 is a PEG lipid conjugated with a fluorophore. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy and flow cytometry. The absorption wavelength of the Cy3 fluorophore peaks at 548-552 nm, while its emission wavelength reaches a maximum at 562-570 nm. DSPE-PEG2000-Cy3 can be used in research areas such as the preparation of nanoparticles and drug delivery .

HY-159194

DSPE-PEG2000-Cy5.5		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer .

HY-177205

DSPE-PEG2000-CRPPR		Pegylated Lipids
DSPE-PEG2000-CRPPR is a polyethylene glycol (PEG) conjugate composed of DSPE and Heart-homing peptide (CRPPR) (HY-P10641). DSPE-PEGs are modified with the CRPPR peptide to bind cysteine-rich protein 2 (CRIP2) as well as FITC-labeled superparamagnetic iron oxide nanoparticles .

HY-155908

DSPE-PEG10000-Amine ammonium DSPE-PEG10000-NH2 ammonium		Pegylated Lipids
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG5000-Amine ammonium DSPE-PEG5000-NH2 ammonium		Pegylated Lipids
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-172273A

DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-160269

DSPE-PEG2000-Fluor 488		Pegylated Lipids Fluorescent Lipids
DSPE-PEG2000-Fluor 488 is a PEG-dye-lipid conjugate consisting of a DSPE phospholipid and a Fluor 488 dye. DSPE is a phospholipid that spontaneously forms micelles in a water medium, and Fluor 488 is a cyanine dye that is widely used in fluorescence microscopy. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm. Polyethylene glycol lipids are commonly used for the stabilization of lipid nanoparticles .

HY-144001

DSPE-PEG-Carboxylic acid ammonium		Pegylated Lipids
DSPE-PEG-Carboxylic acid ammonium is a phospholipid PEG conjugate. DSPE-PEG-Carboxylic Acid can be widely used in the delivery of targeted agents and genes .

HY-144000A

DSPE-PEG2000-PDP		Pegylated Lipids
DSPE-PEG2000-PDP is a phospholipid PEG conjugate that can be used in drug delivery applications .

HY-160280

DOPE-PEG2000-Fluor 647		Pegylated Lipids Fluorescent Lipids
DOPE-PEG2000-Fluor 647 is a PEG-lipid-dye conjugate. composed of a DOPE phospholipid and a Fluor 647 dye .

HY-155934

18:1 PEG5000 PE ammonium DOPE-PEG5000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155926

DMPE-PEG750 ammonium 14:0 PEG750 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium		Pegylated Lipids
DMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155925

DMPE-PEG550 ammonium 14:0 PEG550 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium		Pegylated Lipids
DMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155924

DMPE-PEG350 ammonium 14:0 PEG350 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
DMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155927

DMPE-PEG1000 ammonium 14:0 PEG1000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium		Pegylated Lipids
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155929

DMPE-PEG5000 ammonium 14:0 PEG5000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium		Pegylated Lipids
DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155928

DMPE-PEG3000 ammonium 14:0 PEG3000 PE ammonium; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium		Pegylated Lipids
DMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-W115607

PEG4000-bis-amine Poly(ethylene glycol)-bis-amine 4000		Polymers
PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-144013B

18:0 mPEG550 PE ammonium DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium		Pegylated Lipids
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013A

18:0 mPEG350 PE ammonium DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013D

18:0 mPEG1000 PE ammonium DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium		Pegylated Lipids
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013E

18:0 mPEG3000 PE ammonium DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium		Pegylated Lipids
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-144013C

18:0 mPEG750 PE ammonium DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium		Pegylated Lipids
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-W591632

PEG-bis-amine (MW 1000) Poly(ethylene glycol)-bis-amine (MW 1000)		Polymers
PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).

HY-172273

DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY		Pegylated Lipids
DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG1000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery .

HY-172465

DSPE-PEG5000-cRGD		Pegylated Lipids
DSPE-PEG5000-cRGD is a PEG conjugate composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. DSPE-PEG5000-cRGD is applicable for research on drug delivery, cancer and vascular diseases .

HY-155931

18:1 PEG550 PE ammonium DOPE-PEG550 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium		Pegylated Lipids
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155933

18:1 PEG3000 PE ammonium DOPE-PEG3000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium		Pegylated Lipids
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155932

18:1 PEG1000 PE ammonium DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium		Pegylated Lipids
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

HY-155930

18:1 PEG350 PE ammonium DOPE-PEG350 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium		Pegylated Lipids
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-138300GL

ALC-0159 (GMP Like)	Liposome	Inflammation/Immunology
ALC-0159 (GMP Like) is the GMP Like class ALC-0159 (HY-138300). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-42972G

DBCO-acid	Biochemical Assay Reagents	Cancer
DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

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