2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Thalidomide-4-NH-PEG1-COOH TFA

Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

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Thalidomide-4-NH-PEG1-COOH TFA Chemical Structure

Thalidomide-4-NH-PEG1-COOH TFA Chemical Structure

CAS No. : 2140807-20-9

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Thalidomide-4-NH-PEG1-COOH TFA Related Antibodies

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Description

Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

Molecular Weight

503.38

Formula

C20H20F3N3O9
CAS No.
SMILES

O=C(O)CCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Thalidomide-4-NH-PEG1-COOH TFA Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-4-NH-PEG1-COOH2140807-20-9E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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