Pomalidomide 4'-PEG6-azide
Based on 1 Customer Validation
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs.
For research use only. We do not sell to patients.
- Purity : 98.07%
- CAS No.: 2624181-62-8
- Formula: C27H38N6O10
- Molecular Weight:606.62
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
Cereblon |
Chemical Information
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CAS No. 2624181-62-8
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Appearance Oil
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Molecular Weight 606.62
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Formula C27H38N6O10
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Color Light green to green
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SMILES
[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (82.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6485 mL | 8.2424 mL | 16.4848 mL | 41.2120 mL |
| 5 mM | 0.3297 mL | 1.6485 mL | 3.2970 mL | 8.2424 mL | |
| 10 mM | 0.1648 mL | 0.8242 mL | 1.6485 mL | 4.1212 mL | |
| 15 mM | 0.1099 mL | 0.5495 mL | 1.0990 mL | 2.7475 mL | |
| 20 mM | 0.0824 mL | 0.4121 mL | 0.8242 mL | 2.0606 mL | |
| 25 mM | 0.0659 mL | 0.3297 mL | 0.6594 mL | 1.6485 mL | |
| 30 mM | 0.0549 mL | 0.2747 mL | 0.5495 mL | 1.3737 mL | |
| 40 mM | 0.0412 mL | 0.2061 mL | 0.4121 mL | 1.0303 mL | |
| 50 mM | 0.0330 mL | 0.1648 mL | 0.3297 mL | 0.8242 mL | |
| 60 mM | 0.0275 mL | 0.1374 mL | 0.2747 mL | 0.6869 mL | |
| 80 mM | 0.0206 mL | 0.1030 mL | 0.2061 mL | 0.5151 mL |
Pomalidomide 4'-PEG6-azide Related Classifications
HY-139332 Related Classifications
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