PL1601
PL1601 (BCN-HS-PEG2-VA-PABC-SG3199) is a pyrrolobenzodiazepine that can be used as a agent linker of antibody-drug conjugates (ADC). PL1601 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 2126805-05-6
- Formula: C66H83N9O18S
- Molecular Weight:1322.48
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2126805-05-6
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Appearance Solid
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Molecular Weight 1322.48
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Formula C66H83N9O18S
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Color White to light yellow
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SMILES
O=C(N([C@H]1O)C(C(C(N2[C@@]1([H])CC(C)=C2)=O)=C3)=CC(OCCCCCOC(C=C(N=C[C@@](C4)([H])N(C=C4C)C5=O)C5=C6)=C6OC)=C3OC)OCC(C=C7)=CC=C7NC([C@H](C)NC([C@H](C(C)C)NC(COCCOCCN[S](NC(OC[C@@H]8[C@@]9([H])[C@]8([H])CCC#CCC9)=O)(=O)=O)=O)=O)=O
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Synonyms
BCN-HS-PEG2-VA-PABC-SG3199
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PL1601 Related Classifications
HY-47018 Related Classifications
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