(S,R,S)-AHPC-PEG3-NH2 dihydrochloride
(S,R,S)-AHPC-PEG3-NH2 dihydrochloride (VH032-PEG3-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology
For research use only. We do not sell to patients.
- CAS No.: 2376990-24-6
- Formula: C30H47Cl2N5O7S
- Molecular Weight:692.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-128716B
Pomalidomide-PEG3-C2-NH2 hydrochloride -
HY-103603B
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride -
HY-136161
Pomalidomide-PEG6-NH2 hydrochloride -
HY-136165
(S,R,S)-AHPC-PEG3-propionic acid -
HY-136008A
(S,R,S)-AHPC-PEG1-NH2 dihydrochloride -
HY-136184
(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride -
HY-112618B
Thalidomide-O-amido-C6-NH2 hydrochloride -
HY-128767
VH032-PEG3-acetylene -
HY-103604
(S,R,S)-AHPC-PEG4-NH2 hydrochloride -
HY-136183
(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride -
HY-131872
Pomalidomide-PEG2-COOH -
HY-107438A
Thalidomide-O-amido-C4-NH2 hydrochloride
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2376990-24-6
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Molecular Weight 692.69
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Formula C30H47Cl2N5O7S
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SMILES
[H]Cl.O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C3.[H]Cl
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Synonyms
VH032-PEG3-NH2 dihydrochloride; VHL Ligand-Linker Conjugates 1 dihydrochloride; E3 ligase Ligand-Linker Conjugates 5 dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513. [Content Brief]
[2]. Salami J, et al. Waste disposal-An attractive strategy for cancer therapy. Science. 2017;355(6330):1163-1167. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S,R,S)-AHPC-PEG3-NH2 dihydrochloride Related Classifications
HY-103602B Related Classifications
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