Pomalidomide-PEG6-butyl iodide
Based on 1 Customer Validation
Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology.
For research use only. We do not sell to patients.
- Purity: 97.64%
- CAS No.: 1835705-74-2
- Formula: C31H44IN3O11
- Molecular Weight:761.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1835705-74-2
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Appearance Solid
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Molecular Weight 761.60
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Formula C31H44IN3O11
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Color White to off-white
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SMILES
O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)COCCOCCOCCOCCOCCOCCCCCCI
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (131.30 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3130 mL | 6.5651 mL | 13.1303 mL | 32.8256 mL |
| 5 mM | 0.2626 mL | 1.3130 mL | 2.6261 mL | 6.5651 mL | |
| 10 mM | 0.1313 mL | 0.6565 mL | 1.3130 mL | 3.2826 mL | |
| 15 mM | 0.0875 mL | 0.4377 mL | 0.8754 mL | 2.1884 mL | |
| 20 mM | 0.0657 mL | 0.3283 mL | 0.6565 mL | 1.6413 mL | |
| 25 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL | 1.3130 mL | |
| 30 mM | 0.0438 mL | 0.2188 mL | 0.4377 mL | 1.0942 mL | |
| 40 mM | 0.0328 mL | 0.1641 mL | 0.3283 mL | 0.8206 mL | |
| 50 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6565 mL | |
| 60 mM | 0.0219 mL | 0.1094 mL | 0.2188 mL | 0.5471 mL | |
| 80 mM | 0.0164 mL | 0.0821 mL | 0.1641 mL | 0.4103 mL | |
| 100 mM | 0.0131 mL | 0.0657 mL | 0.1313 mL | 0.3283 mL |
Pomalidomide-PEG6-butyl iodide Related Classifications
HY-136156 Related Classifications
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