2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Thalidomide-PEG2-C2-NH2 hydrochloride

Thalidomide-PEG2-C2-NH2 hydrochloride  (Synonyms: Thalidomide-NH-PEG2-C2-NH2 hydrochloride)

Cat. No.: HY-129703B
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Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

For research use only. We do not sell to patients.

Thalidomide-PEG2-C2-NH2 hydrochloride Chemical Structure

Thalidomide-PEG2-C2-NH2 hydrochloride Chemical Structure

CAS No. : 2245697-87-2

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Based on 1 publication(s) in Google Scholar

Other Forms of Thalidomide-PEG2-C2-NH2 hydrochloride:

Thalidomide-PEG2-C2-NH2 hydrochloride Related Antibodies

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View All E3 Ligase Ligand-Linker Conjugates Isoform Specific Products:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

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Description

Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thalidomide-PEG2-C2-NH2 hydrochloride Related Antibodies
Molecular Weight

440.88

Formula

C19H25ClN4O6
CAS No.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCN)=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Thalidomide-PEG2-C2-NH2 hydrochloride Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-PEG2-C2-NH22245697-87-2Thalidomide-NH-PEG2-C2-NH2E3 Ligase Ligand-Linker ConjugatesE3ligaseligand-linkerconjugatePEG3PROTACInhibitorinhibitorinhibit

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