cFLFLF
Based on 1 Customer Validation
cFLFLF is a FPR-specific peptide. cFLFLF is sequentially conjugated with a bifunctional polyethylene glycol moiety (PEG, 3.4 kD) and a DOTA through a lysine (K) spacer and finally labeled with 64Cu-CuCl2 to form cFLFLFKPEG-64Cu. cFLFLFKPEG-64Cu is a neutrophil-specific PET imaging agent.
For research use only. We do not sell to patients.
- CAS No.: 1000977-62-7
- Formula: C54H70N8O7
- Molecular Weight:943.18
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
Description
In Vitro
cFLFLF is sequentially conjugated with a bifunctional polyethylene glycol moiety (PEG, 3.4 kD) and a DOTA through a lysine (K) spacer and finally labeled with 64Cu-CuCl2 to form cFLFLFKPEG-64Cu. cFLFLFKPEG-64Cu is a neutrophil-specific PET imaging agent[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 1000977-62-7
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Appearance Solid
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Molecular Weight 943.18
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Formula C54H70N8O7
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Sequence
{Cinnamoyl}-Phe-{D-Leu}-Phe-{D-Leu}-Phe-Lys-NH2
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Sequence Shortening
{Cinnamoyl}-F-{D-Leu}-F-{D-Leu}-FK-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (106.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0602 mL | 5.3012 mL | 10.6024 mL | 26.5061 mL |
| 5 mM | 0.2120 mL | 1.0602 mL | 2.1205 mL | 5.3012 mL | |
| 10 mM | 0.1060 mL | 0.5301 mL | 1.0602 mL | 2.6506 mL | |
| 15 mM | 0.0707 mL | 0.3534 mL | 0.7068 mL | 1.7671 mL | |
| 20 mM | 0.0530 mL | 0.2651 mL | 0.5301 mL | 1.3253 mL | |
| 25 mM | 0.0424 mL | 0.2120 mL | 0.4241 mL | 1.0602 mL | |
| 30 mM | 0.0353 mL | 0.1767 mL | 0.3534 mL | 0.8835 mL | |
| 40 mM | 0.0265 mL | 0.1325 mL | 0.2651 mL | 0.6627 mL | |
| 50 mM | 0.0212 mL | 0.1060 mL | 0.2120 mL | 0.5301 mL | |
| 60 mM | 0.0177 mL | 0.0884 mL | 0.1767 mL | 0.4418 mL | |
| 80 mM | 0.0133 mL | 0.0663 mL | 0.1325 mL | 0.3313 mL | |
| 100 mM | 0.0106 mL | 0.0530 mL | 0.1060 mL | 0.2651 mL |