Amino-PEG3-2G degrader-1
Amino-PEG3-2G degrader-1 (compound ) is a conjugate of a PEG Linker and a pyrazole-linked FBnG tag for ubiquitin-proteasome system (UPS) induction. Amino-PEG3-2G degrader-1 can be used to synthesize autophagy-targeting chimeras (AUTACs).
For research use only. We do not sell to patients.
- CAS No.: 2267315-06-8
- Formula: C25H33FN8O4
- Molecular Weight:528.58
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2267315-06-8
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Appearance Solid
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Molecular Weight 528.58
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Formula C25H33FN8O4
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Color White to off-white
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SMILES
O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCCOCCOCCOCCCN)N=C4)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (189.19 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8919 mL | 9.4593 mL | 18.9186 mL | 47.2965 mL |
| 5 mM | 0.3784 mL | 1.8919 mL | 3.7837 mL | 9.4593 mL | |
| 10 mM | 0.1892 mL | 0.9459 mL | 1.8919 mL | 4.7297 mL | |
| 15 mM | 0.1261 mL | 0.6306 mL | 1.2612 mL | 3.1531 mL | |
| 20 mM | 0.0946 mL | 0.4730 mL | 0.9459 mL | 2.3648 mL | |
| 25 mM | 0.0757 mL | 0.3784 mL | 0.7567 mL | 1.8919 mL | |
| 30 mM | 0.0631 mL | 0.3153 mL | 0.6306 mL | 1.5766 mL | |
| 40 mM | 0.0473 mL | 0.2365 mL | 0.4730 mL | 1.1824 mL | |
| 50 mM | 0.0378 mL | 0.1892 mL | 0.3784 mL | 0.9459 mL | |
| 60 mM | 0.0315 mL | 0.1577 mL | 0.3153 mL | 0.7883 mL | |
| 80 mM | 0.0236 mL | 0.1182 mL | 0.2365 mL | 0.5912 mL | |
| 100 mM | 0.0189 mL | 0.0946 mL | 0.1892 mL | 0.4730 mL |
Amino-PEG3-2G degrader-1 Related Classifications
HY-158985 Related Classifications
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