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Cat. No.: HY-179327

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N-(Hexanoyloxy)succinimide-MMAE

N-(Hexanoyloxy)succinimide-MMAE is a conjugate of the ADC drug toxin molecule and the linker, containing a degradable PEG linker and the toxin molecule MMAE (HY-15162).

For research use only. We do not sell to patients.

CAS No.: 1404073-15-9
Formula: C₄₉H₈₀N₆O₁₁
Molecular Weight:929.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

N-(Hexanoyloxy)succinimide-MMAE Chemical Structure

CAS No.: 1404073-15-9

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Description

N-(Hexanoyloxy)succinimide-MMAE is a conjugate of the ADC drug toxin molecule and the linker, containing a degradable PEG linker and the toxin molecule MMAE (HY-15162)^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 1404073-15-9
Molecular Weight 929.19
Formula C₄₉H₈₀N₆O₁₁
SMILES

O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCCCC(ON3C(CCC3=O)=O)=O)=O)=O)=O)OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hans-Georg Lerchen, et al. Novel binder-drug conjugates (adcs) and their use. WO2012143495A2.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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