Ledadotin
Ledadotin is a drug-linker conjugate for ADC. Ledadotin consists of a Microtubule inhibitor (Auristatin F-hydroxypropylamide) (HY-P5191) and a linker (BCN-PEG2-Gly-NH-tri(βAla-GGGG-Ser(mPEG8)-βAla-γGlu-Ala)) (HY-177562). Ledadotin can be used for synthesis of ADC Emiltatug ledadotin (HY-177542).
For research use only. We do not sell to patients.
- CAS No.: 2669084-60-8
- Formula: C294H494N52O100
- Molecular Weight:6357.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 2669084-60-8
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Molecular Weight 6357.36
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Formula C294H494N52O100
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SMILES
O=C(NCCC(NCC(NCC(NCC(NCC(N[C@H](C(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COC(NCCC(N[C@H](C(O)=O)CCC(N[C@H](C(OCCCNC([C@@H](CC1=CC=CC=C1)NC([C@H]([C@H](OC)[C@H]2CCCN2C(C[C@@H]([C@@H]([C@@H](CC)C)N(C([C@@H](C(C)C)NC([C@@H](C(C)C)N(C)C)=O)=O)C)OC)=O)C)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)CCOCC(COCCC(NCCC(NCC(NCC(NCC(NCC(N[C@H](C(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COC(NCCC(N[C@H](C(O)=O)CCC(N[C@H](C(OCCCNC([C@@H](CC3=CC=CC=C3)NC([C@H]([C@H](OC)[C@H]4CCCN4C(C[C@@H]([C@@H]([C@@H](CC)C)N(C([C@@H](C(C)C)NC([C@@H](C(C)C)N(C)C)=O)=O)C)OC)=O)C)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)(COCCC(NCCC(NCC(NCC(NCC(NCC(N[C@H](C(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COC(NCCC(N[C@H](C(O)=O)CCC(N[C@H](C(OCCCNC([C@@H](CC5=CC=CC=C5)NC([C@H]([C@H](OC)[C@H]6CCCN6C(C[C@@H]([C@@H]([C@@H](CC)C)N(C([C@@H](C(C)C)NC([C@@H](C(C)C)N(C)C)=O)=O)C)OC)=O)C)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC(CNC(CCC(NCCOCCOCCNC(OC[C@H]7[C@]8(CCC#CCC[C@]87[H])[H])=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ledadotin Related Classifications
HY-177541 Related Classifications
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