1. Antibody-drug Conjugate/ADC Related PROTAC
  2. Drug-Linker Conjugates for ADC E3 Ligase Ligand-Linker Conjugates
  3. Thalidomide-NH-PEG7

Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader.

For research use only. We do not sell to patients.

Thalidomide-NH-PEG7 Chemical Structure

Thalidomide-NH-PEG7 Chemical Structure

CAS No. : 2641838-98-2

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Description

Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader[1].

IC50 & Target

Cereblon

 

Molecular Weight

581.61

Formula

C27H39N3O11

CAS No.
SMILES

OCCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Thalidomide-NH-PEG7
Cat. No.:
HY-130648
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