C18-PEG2000-Mal 

C18-PEG2000-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG2000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.

The structure of C18-PEG-Mal comprises three key parts that work synergistically:
C18: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, to achieve targeting or tracing functions.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2000 (Average)

O=C(NCCOCCNC(CCN1C(C=CC1=O)=O)=O)CCCCCCCCCCCCCCCCC.[n]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.