C18-PEG3400-Mal
C18-PEG3400-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG3400-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
For research use only. We do not sell to patients.
- Molecular Weight:3400 (Average)
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Biological Activity
The structure of C18-PEG-Mal comprises three key parts that work synergistically:
C18: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, to achieve targeting or tracing functions.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 3400 (Average)
-
SMILES
O=C(NCCOCCNC(CCN1C(C=CC1=O)=O)=O)CCCCCCCCCCCCCCCCC.[n]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz