C16-PEG5000-Mal
C16-PEG5000-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG5000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
For research use only. We do not sell to patients.
- Molecular Weight:5000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of C16-PEG-Mal comprises three key parts that work synergistically:
C16: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, to achieve targeting or tracing functions.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 5000 (Average)
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SMILES
CCCCCCCCCCCCCCCC(NCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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