1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. E3 Ligase Ligand-Linker Conjugates 53

E3 Ligase Ligand-Linker Conjugates 53 

Cat. No.: HY-125883
Handling Instructions

Ligand-Linker Conjugates 53 incorporates a cereblon (CRBN) ligand pomalidomide for the E3 ubiquitin ligase, and a PROTAC linker, used in PROTAC technology.

For research use only. We do not sell to patients.

E3 Ligase Ligand-Linker Conjugates 53 Chemical Structure

E3 Ligase Ligand-Linker Conjugates 53 Chemical Structure

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Description

Ligand-Linker Conjugates 53 incorporates a cereblon (CRBN) ligand pomalidomide for the E3 ubiquitin ligase, and a PROTAC linker, used in PROTAC technology[1].

IC50 & Target

Cereblon

 

Molecular Weight

631.67

Formula

C₃₀H₄₁N₅O₁₀

SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NC(CCCCC(NCCOCCOCCNC(OC(C)(C)C)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
E3 Ligase Ligand-Linker Conjugates 53
Cat. No.:
HY-125883
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