DSPE-PEG2000-Cy5.5
Based on 1 publication(s) in Google Scholar
DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer.
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- Fòrmula: C176H311N4O55P
- Peso molecular:3394.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Publications Citing Use of MedChemExpress (MCE) DSPE-PEG2000-Cy5.5
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Actividad biológica
DSPE-PEG2000-Cy5.5 (6.5 mM lipid concentration in FBS; 96 h at 37°C) containing liposomes release less than 25% of their Cy5.5 content over 96 hours of incubation at 37°C in fetal bovine serum[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CD-1 (athymic female, 6 weeks old, average weight 27 g)[1]
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Dosage:1.8 g lipid/kg body weight (containing DSPE-PEG2000-Cy5.5 at a molar ratio of 0.02 relative to total lipids)
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Administration:tail vein; single injection
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Result:Exhibited a vascular half-life of 36.2 hours.
Showed statistically significant higher accumulation in the liver at 5 minutes and 24 hours postinjection compared to CT-only liposomes.
Showed statistically significant higher accumulation in the kidneys at 48, 72, and 96 hours postinjection compared to CT-only liposomes.
Had accumulation in the spleen equivalent to CT-only liposomes.
Chemical Information
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Peso molecular 3394.32
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Fòrmula C176H311N4O55P
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SMILES
O=C(OC[C@]([H])(COP(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC[N+]1=C(C(C)(C2=C1C=CC3=CC=CC=C23)C)/C=C/C=C/C=C4N(C5=C(C/4(C)C)C6=CC=CC=C6C=C5)C)=O)=O)([O-])=O)OC(CCCCCCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCCCCCC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
Programmable nanomotor system responsively and chemotactically captures tumor associated antigens for enhanced in situ cancer vaccine. [Abstract]2025 Nov 11:35:102543. PMID: 41322135
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSPE-PEG2000-Cy5.5 Related Classifications
HY-159194 Related Classifications
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