DSPE-PEG2000-Cy5.5
Based on 1 publication(s) in Google Scholar
DSPE-PEG2000-Cy5.5 is a phospholipid-fluorophore conjugate consisting of Cy5.5 covalently linked to 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), serving as a surface label for liposomes in multimodal CT/optical imaging.DSPE-PEG2000-Cy5.5 can be used for the research of non-small cell lung cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 95.0%
- 분자량:2000 (average)
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DSPE-PEG2000-Cy5.5
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Biological Activity
제품 설명
In Vitro
DSPE-PEG2000-Cy5.5 (6.5 mM lipid concentration in FBS; 96 h at 37°C) containing liposomes release less than 25% of their Cy5.5 content over 96 hours of incubation at 37°C in fetal bovine serum[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CD-1 (athymic female, 6 weeks old, average weight 27 g)[1]
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Dosage:1.8 g lipid/kg body weight (containing DSPE-PEG2000-Cy5.5 at a molar ratio of 0.02 relative to total lipids)
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Administration:tail vein; single injection
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Result:Exhibited a vascular half-life of 36.2 hours.
Showed statistically significant higher accumulation in the liver at 5 minutes and 24 hours postinjection compared to CT-only liposomes.
Showed statistically significant higher accumulation in the kidneys at 48, 72, and 96 hours postinjection compared to CT-only liposomes.
Had accumulation in the spleen equivalent to CT-only liposomes.
Chemical Information
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Appearance Solid
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분자량 2000 (average)
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Color Blue to dark blue
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SMILES
CCCCCCCCCCCCCCCCCC(OC[C@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCNC(CCCCC[N+]1=C(/C=C/C=C/C=C2N(C)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56)=O)=O)([O-])=O)=O.[45]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
Programmable nanomotor system responsively and chemotactically captures tumor associated antigens for enhanced in situ cancer vaccine. [Abstract]2025 Nov 11:35:102543. PMID: 41322135
용액&용해도
In Vitro:
DMSO : 20 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
순도&문서
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
DSPE-PEG2000-Cy5.5 Related Classifications
HY-159194 Related Classifications
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