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  3. Mannose-PEG1000-COOH

Mannose-PEG1000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

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Mannose-PEG1000-COOH

Mannose-PEG1000-COOH Chemical Structure

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Description

Mannose-PEG1000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

In Vitro

The structure of Mannose-PEG-COOH contains three key parts, which work synergistically:
Mannose: As a targeting navigator, it can specifically recognize and bind to "mannose receptors" on the cell surface.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Carboxyl group (-COOH): Located at the end of the PEG chain, it is a reaction interface capable of condensation or esterification reactions with amino groups, hydroxyl groups, etc.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SMILES

OC[C@@H]1OC(O)[C@H](NC(COCCOCC(O)=O)=O)[C@H](O)[C@H]1O.[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mannose-PEG1000-COOH
Cat. No.:
HY-183003
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