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Cat. No.: HY-181043

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CRBN ligand-895-PEG2-N3

CRBN ligand-895-PEG2-N3 (Compound 15) is a synthetic E3 ligase linker conjugate that can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024).

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CAS No.: 3052115-00-8
Formule: C₁₉H₂₅N₅O₆
Masse moléculaire:419.43

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

CRBN ligand-895-PEG2-N3 Chemical Structure

CAS No.: 3052115-00-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

CRBN ligand-895-PEG2-N3 (Compound 15) is a synthetic E3 ligase linker conjugate that can be used for the synthesis of PROTACs, such as PROTAC HDAC8 Degrader-4 (HY-181024)^[1].

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Chemical Information

CAS No. 3052115-00-8
Masse moléculaire 419.43
Formule C₁₉H₂₅N₅O₆
SMILES

O=C(C(CC1)C2=CC=C(C=C2)OCC(NCCOCCOCCN=[N+]=[N-])=O)NC1=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhai S, et al. Discovery of Histone Deacetylase 8-Specific Proteolysis-Targeting Chimeras with Anticancer Activity against Hematological Malignancies. J Med Chem. 2026 Jan 22;69(2):918-943. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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CRBN ligand-895-PEG2-N3

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CRBN ligand-895-PEG2-N3 Related Classifications

HY-181043 Related Classifications