Pom-8PEG
Based on 1 Customer Validation
Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader.
For research use only. We do not sell to patients.
- Purity: 95.09%
- CAS No.: 2488761-03-9
- Formula: C29H43N3O12
- Molecular Weight:625.66
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2488761-03-9
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Appearance Viscous Liquid
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Molecular Weight 625.66
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Formula C29H43N3O12
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Color Light green to green
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCOCCOCCOCCO)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (159.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5983 mL | 7.9916 mL | 15.9831 mL | 39.9578 mL |
| 5 mM | 0.3197 mL | 1.5983 mL | 3.1966 mL | 7.9916 mL | |
| 10 mM | 0.1598 mL | 0.7992 mL | 1.5983 mL | 3.9958 mL | |
| 15 mM | 0.1066 mL | 0.5328 mL | 1.0655 mL | 2.6639 mL | |
| 20 mM | 0.0799 mL | 0.3996 mL | 0.7992 mL | 1.9979 mL | |
| 25 mM | 0.0639 mL | 0.3197 mL | 0.6393 mL | 1.5983 mL | |
| 30 mM | 0.0533 mL | 0.2664 mL | 0.5328 mL | 1.3319 mL | |
| 40 mM | 0.0400 mL | 0.1998 mL | 0.3996 mL | 0.9989 mL | |
| 50 mM | 0.0320 mL | 0.1598 mL | 0.3197 mL | 0.7992 mL | |
| 60 mM | 0.0266 mL | 0.1332 mL | 0.2664 mL | 0.6660 mL | |
| 80 mM | 0.0200 mL | 0.0999 mL | 0.1998 mL | 0.4995 mL | |
| 100 mM | 0.0160 mL | 0.0799 mL | 0.1598 mL | 0.3996 mL |
Pom-8PEG Related Classifications
HY-132288 Related Classifications
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