Thalidomide-O-PEG5-alkyne
Thalidomide-O-PEG5-alkyne is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2411681-90-6
- Formula: C26H30N2O11
- Molecular Weight:546.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2411681-90-6
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Molecular Weight 546.53
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Formula C26H30N2O11
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SMILES
O=C(OCCOCCOCCOCCOCC#C)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-O-PEG5-alkyne Related Classifications
HY-W190931 Related Classifications
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