Mal-PEG8-Val-Ala-PAB-SB-743921
Based on 1 Customer Validation
Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 99.28%
- Formula: C73H96ClN7O19
- Molecular Weight:1411.03
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Oil
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Molecular Weight 1411.03
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Formula C73H96ClN7O19
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Color Colorless to light yellow
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SMILES
O=C1C2=CC=C(Cl)C=C2OC([C@@H](C(C)C)N(C(C3=CC=C(C)C=C3)=O)CCCNC(OCC4=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN5C(C=CC5=O)=O)=O)=O)=O)=O)C=C4)=O)=C1CC6=CC=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (70.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7087 mL | 3.5435 mL | 7.0870 mL | 17.7176 mL |
| 5 mM | 0.1417 mL | 0.7087 mL | 1.4174 mL | 3.5435 mL | |
| 10 mM | 0.0709 mL | 0.3544 mL | 0.7087 mL | 1.7718 mL | |
| 15 mM | 0.0472 mL | 0.2362 mL | 0.4725 mL | 1.1812 mL | |
| 20 mM | 0.0354 mL | 0.1772 mL | 0.3544 mL | 0.8859 mL | |
| 25 mM | 0.0283 mL | 0.1417 mL | 0.2835 mL | 0.7087 mL | |
| 30 mM | 0.0236 mL | 0.1181 mL | 0.2362 mL | 0.5906 mL | |
| 40 mM | 0.0177 mL | 0.0886 mL | 0.1772 mL | 0.4429 mL | |
| 50 mM | 0.0142 mL | 0.0709 mL | 0.1417 mL | 0.3544 mL | |
| 60 mM | 0.0118 mL | 0.0591 mL | 0.1181 mL | 0.2953 mL |
Mal-PEG8-Val-Ala-PAB-SB-743921 Related Classifications
HY-149416 Related Classifications
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