Glucose-PEG2000-COOH
Glucose-PEG2000-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG2000-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
The structure of Glucose-PEG-COOH comprises three key parts that work synergistically:
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), enabling receptor-mediated active targeted delivery.
PEG Chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Carboxyl Group (-COOH): A reaction interface located at the end of the PEG chain, capable of condensation or esterification reactions with amino and hydroxyl groups.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
OC1O[C@H]([C@@H]([C@H]([C@@H]1NC(OCCOCC(O)=O)=O)O)O)CO.[n]
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Glucose-PEG2000-COOH Related Classifications
HY-183163A Related Classifications
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