Pomalidomide-PEG1-NH2 hydrochloride
Based on 1 Customer Validation
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand.
For research use only. We do not sell to patients.
- Purity: 97.05%
- CAS No.: 2380273-67-4
- Formula: C17H19ClN4O6
- Molecular Weight:410.81
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2380273-67-4
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Appearance Solid
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Molecular Weight 410.81
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Formula C17H19ClN4O6
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Color Light yellow to yellow
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SMILES
[H]Cl.NCCOCC(NC1=CC=CC(C2=O)=C1C(N2C(C3=O)CCC(N3)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 62.5 mg/mL (152.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4342 mL | 12.1711 mL | 24.3422 mL | 60.8554 mL |
| 5 mM | 0.4868 mL | 2.4342 mL | 4.8684 mL | 12.1711 mL | |
| 10 mM | 0.2434 mL | 1.2171 mL | 2.4342 mL | 6.0855 mL | |
| 15 mM | 0.1623 mL | 0.8114 mL | 1.6228 mL | 4.0570 mL | |
| 20 mM | 0.1217 mL | 0.6086 mL | 1.2171 mL | 3.0428 mL | |
| 25 mM | 0.0974 mL | 0.4868 mL | 0.9737 mL | 2.4342 mL | |
| 30 mM | 0.0811 mL | 0.4057 mL | 0.8114 mL | 2.0285 mL | |
| 40 mM | 0.0609 mL | 0.3043 mL | 0.6086 mL | 1.5214 mL | |
| 50 mM | 0.0487 mL | 0.2434 mL | 0.4868 mL | 1.2171 mL | |
| 60 mM | 0.0406 mL | 0.2029 mL | 0.4057 mL | 1.0143 mL | |
| 80 mM | 0.0304 mL | 0.1521 mL | 0.3043 mL | 0.7607 mL | |
| 100 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6086 mL |