Bis-sulfone-PEG8-NHS ester

Bis-sulfone-PEG8-NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The hydrophilic PEG spacer increases solubility in aqueous media.

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  • CAS No.: 2363757-66-6
  • 화학식: C48H64N2O18S2
  • 분자량:1021.15
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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