C18-PEG5000-COOH 

C18-PEG5000-COOH is a conjugate composed of an octadecyl group (C18 aliphatic chain), a PEG chain, and a carboxyl group (-COOH). C18-PEG5000-COOH combines the membrane compatibility of lipids with the carboxyl group, which can form amide bonds with primary amines via EDC/NHS activation, making it suitable for research in biomaterial construction and drug delivery.

The structure of C18-PEG-COOH comprises three key parts, each acting synergistically:
C18: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: Serving as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Carboxyl group (-COOH): Located at the end of the PEG chain, it acts as a reaction interface, capable of condensation or esterification reactions with amino groups, hydroxyl groups, etc.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5000 (Average)

O=C(NCCOCC(O)=O)CCCCCCCCCCCCCCCCC.[n]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.