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Cat. No.: HY-103606R

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(S,R,S)-AHPC-PEG6-C4-Cl (Standard)

Name: (S,R,S)-AHPC-PEG6-C4-Cl (Standard)
Brand: MedChemExpress
SKU: HY-103606R
Availability: PreOrder

(Synonyms: VH032-PEG6-C4-Cl (Standard); VHL Ligand-Linker Conjugates 10 (Standard); E3 ligase Ligand-Linker Conjugates 9 (Standard))

(S,R,S)-AHPC-PEG6-C4-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-PEG6-C4-Cl (HY-103606). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG6-C4-Cl is a conjugate of ligands for E3 and 25-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-PEG6-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

For research use only. We do not sell to patients.

CAS No.: 1835705-59-3
Formula: C₄₀H₆₃ClN₄O₁₀S
Molecular Weight:827.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S,R,S)-AHPC-PEG6-C4-Cl (Standard) Chemical Structure

CAS No.: 1835705-59-3

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1835705-59-3
Molecular Weight 827.47
Formula C₄₀H₆₃ClN₄O₁₀S
SMILES

O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCCCCCCCl)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Synonyms

VH032-PEG6-C4-Cl (Standard); VHL Ligand-Linker Conjugates 10 (Standard); E3 ligase Ligand-Linker Conjugates 9 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Tovell H, et al. Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader. ACS Chem Biol. 2019 May 17;14(5):882-892. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(S,R,S)-AHPC-PEG6-C4-Cl (Standard)

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