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  3. (S,R,S)-AHPC-PEG6-C4-Cl

(S,R,S)-AHPC-PEG6-C4-Cl (Synonyms: VH032-PEG6-C4-Cl; VHL Ligand-Linker Conjugates 10; E3 ligase Ligand-Linker Conjugates 9)

Cat. No.: HY-103606 Purity: 96.46%
Handling Instructions

(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays.

For research use only. We do not sell to patients.

(S,R,S)-AHPC-PEG6-C4-Cl Chemical Structure

(S,R,S)-AHPC-PEG6-C4-Cl Chemical Structure

CAS No. : 1835705-59-3

Size Price Stock Quantity
100 mg USD 550 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
1 g USD 3350 In-stock
Estimated Time of Arrival: December 31
2 g USD 4900 In-stock
Estimated Time of Arrival: December 31
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Description

(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. (S,R,S)-AHPC-PEG6-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

IC50 & Target

VHL

 

In Vitro

HaloPROTACs are designed to induce ubiquitylation and degradation of HaloTag7 fusion proteins[1].

Molecular Weight

827.47

Formula

C₄₀H₆₃ClN₄O₁₀S

CAS No.

1835705-59-3

SMILES

O=C([[email protected]]1N(C([[email protected]](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCCCCCCCl)=O)=O)C[[email protected]](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
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Keywords:

(S,R,S)-AHPC-PEG6-C4-ClVH032-PEG6-C4-ClVHL Ligand-Linker Conjugates 10E3 ligase Ligand-Linker Conjugates 9PROTACProteolysis-targeting chimeraInhibitorinhibitorinhibit

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Product name:
(S,R,S)-AHPC-PEG6-C4-Cl
Cat. No.:
HY-103606
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