Amine-PEG3-Lys(PEG3-N3)-PEG3-N3

Cat. No.: HY-153672 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 Chemical Structure

CAS No. : 2244602-35-3

Size	Price	Stock	Quantity
5 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 500	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 800	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1280	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 (compound 5) is a branched linker that can be used in the synthesis of antibody-drug conjugates (ADCs)^[1].

Molecular Weight

750.84

Formula

C₃₀H₅₈N₁₀O₁₂

CAS No.

2244602-35-3

Appearance

Oil

Color

Yellow to brown

SMILES

O=C(NCCOCCOCCOCCN=[N+]=[N-])[C@H](CCCCNC(COCCOCCOCCN=[N+]=[N-])=O)NC(COCCOCCOCCN)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (133.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3318 mL	6.6592 mL	13.3184 mL
5 mM	0.2664 mL	1.3318 mL	2.6637 mL
10 mM	0.1332 mL	0.6659 mL	1.3318 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (243 KB) HNMR (116 KB) LCMS (367 KB)

Handling Instructions (2659 KB)

References

[1]. Anami Y, et, al. Enzymatic conjugation using branched linkers for constructing homogeneous antibody-drug conjugates with high potency. Org Biomol Chem. 2017 Jul 5;15(26):5635-5642. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3318 mL	6.6592 mL	13.3184 mL	33.2960 mL
	5 mM	0.2664 mL	1.3318 mL	2.6637 mL	6.6592 mL
	10 mM	0.1332 mL	0.6659 mL	1.3318 mL	3.3296 mL
	15 mM	0.0888 mL	0.4439 mL	0.8879 mL	2.2197 mL
	20 mM	0.0666 mL	0.3330 mL	0.6659 mL	1.6648 mL
	25 mM	0.0533 mL	0.2664 mL	0.5327 mL	1.3318 mL
	30 mM	0.0444 mL	0.2220 mL	0.4439 mL	1.1099 mL
	40 mM	0.0333 mL	0.1665 mL	0.3330 mL	0.8324 mL
	50 mM	0.0266 mL	0.1332 mL	0.2664 mL	0.6659 mL
	60 mM	0.0222 mL	0.1110 mL	0.2220 mL	0.5549 mL
	80 mM	0.0166 mL	0.0832 mL	0.1665 mL	0.4162 mL
	100 mM	0.0133 mL	0.0666 mL	0.1332 mL	0.3330 mL