Lys(MMT)-PAB-oxydiacetamide-PEG8-N3
Based on 1 Customer Validation
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs). Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Purity : 95.05%
- CAS No.: 1224601-12-0
- Formula: C55H77N7O14
- Molecular Weight:1060.24
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1224601-12-0
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Appearance Oil
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Molecular Weight 1060.24
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Formula C55H77N7O14
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Color Light yellow to yellow
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SMILES
O=C(NC1=CC=C(CO)C=C1)[C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)CCCCNC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (94.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9432 mL | 4.7159 mL | 9.4318 mL | 23.5796 mL |
| 5 mM | 0.1886 mL | 0.9432 mL | 1.8864 mL | 4.7159 mL | |
| 10 mM | 0.0943 mL | 0.4716 mL | 0.9432 mL | 2.3580 mL | |
| 15 mM | 0.0629 mL | 0.3144 mL | 0.6288 mL | 1.5720 mL | |
| 20 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1790 mL | |
| 25 mM | 0.0377 mL | 0.1886 mL | 0.3773 mL | 0.9432 mL | |
| 30 mM | 0.0314 mL | 0.1572 mL | 0.3144 mL | 0.7860 mL | |
| 40 mM | 0.0236 mL | 0.1179 mL | 0.2358 mL | 0.5895 mL | |
| 50 mM | 0.0189 mL | 0.0943 mL | 0.1886 mL | 0.4716 mL | |
| 60 mM | 0.0157 mL | 0.0786 mL | 0.1572 mL | 0.3930 mL | |
| 80 mM | 0.0118 mL | 0.0589 mL | 0.1179 mL | 0.2947 mL |
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 Related Classifications
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