DMPE-PEG1000-NH2
DMPE-PEG1000-NH2 (DMPE-PEG1000-Amine) is a conjugate composed of DMPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DMPE-PEG1000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
The structure of DMPE-PEG-NH2 comprises three key components that work synergistically:
DMPE: Acts as a hydrophobic anchor, responsible for securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Primary amino group (-NH2): A reaction interface located at the end of the PEG chain, enabling coupling with various molecules via a mild and efficient chemical method, such as amidation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
CCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCC)=O)COP(OCCNC(OCCOCCN)=O)(O)=O)=O.[n]
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別名
DMPE-PEG1000-Amine
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)