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Cat. No.: HY-183135A

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C16-PEG3400-Mal

C16-PEG3400-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG3400-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.

For research use only. We do not sell to patients.

Molecular Weight:3400 (Average)

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

C16-PEG3400-Mal Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

The structure of C16-PEG-Mal comprises three key parts that work synergistically:
C16: The long-chain alkyl group imparts significant hydrophobicity to the molecule, enabling self-assembly and allowing it to form micelles, vesicles, or embed in lipid bilayers in aqueous environments.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, to achieve targeting or tracing functions.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 3400 (Average)
SMILES

CCCCCCCCCCCCCCCC(NCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.