1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. N3-PEG8-Phe-Lys-PABC-Gefitinib

N3-PEG8-Phe-Lys-PABC-Gefitinib 

Cat. No.: HY-131088
Handling Instructions

N3-PEG8-Phe-Lys-PABC-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, Gefitinib (orally active EGFR tyrosine kinase inhibitor), linked via the cleavable linker N3-PEG8-Phe-Lys-PABC.

For research use only. We do not sell to patients.

N3-PEG8-Phe-Lys-PABC-Gefitinib Chemical Structure

N3-PEG8-Phe-Lys-PABC-Gefitinib Chemical Structure

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Description

N3-PEG8-Phe-Lys-PABC-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, Gefitinib (orally active EGFR tyrosine kinase inhibitor), linked via the cleavable linker N3-PEG8-Phe-Lys-PABC.

IC50 & Target

Traditional Cytotoxic Agents

 

Molecular Weight

1250.80

Formula

C₆₀H₈₁ClFN₁₁O₁₅

SMILES

ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCNC(OCC4=CC=C(NC([[email protected]](CCCCN)NC([[email protected]@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)CC5=CC=CC=C5)=O)=O)C=C4)=O)=C1)F

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

N3-PEG8-Phe-Lys-PABC-GefitinibDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Product name:
N3-PEG8-Phe-Lys-PABC-Gefitinib
Cat. No.:
HY-131088
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