APN-PEG5-VC-PAB-MMAE
Based on 1 Customer Validation
APN-PEG5-VC-PAB-MMAE is a drug-linker conjugate part of INA03 (a transferrin-competitive antibody-drug conjugate against CD71).
For research use only. We do not sell to patients.
- Purity: 95.19%
- CAS No.: 2252392-31-5
- Formula: C81H120N14O18
- Molecular Weight:1577.90
-
Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2252392-31-5
-
Appearance Solid
-
Molecular Weight 1577.90
-
Formula C81H120N14O18
-
Color White to off-white
-
SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCC(N=N4)=CN4C5=CC=C(C#CC#N)C=C5)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)=O)=O)=O)OC)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (31.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6338 mL | 3.1688 mL | 6.3375 mL | 15.8438 mL |
| 5 mM | 0.1268 mL | 0.6338 mL | 1.2675 mL | 3.1688 mL | |
| 10 mM | 0.0634 mL | 0.3169 mL | 0.6338 mL | 1.5844 mL | |
| 15 mM | 0.0423 mL | 0.2113 mL | 0.4225 mL | 1.0563 mL | |
| 20 mM | 0.0317 mL | 0.1584 mL | 0.3169 mL | 0.7922 mL | |
| 25 mM | 0.0254 mL | 0.1268 mL | 0.2535 mL | 0.6338 mL | |
| 30 mM | 0.0211 mL | 0.1056 mL | 0.2113 mL | 0.5281 mL |
Powered by Bioz