DBCO-PEG3-Glu-Val-Cit-PABC-MMAE
Based on 1 Customer Validation
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG3-Glu-Val-Cit-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162) and can be used for synthesis of dual-drug ADC.
For research use only. We do not sell to patients.
- Purity: 97.69%
- CAS No.: 2861998-23-2
- Formula: C90H129N13O21
- Molecular Weight:1729.06
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2861998-23-2
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Appearance Solid
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Molecular Weight 1729.06
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Formula C90H129N13O21
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Color White to off-white
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SMILES
O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC(COCCOCCOCCNC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (57.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5783 mL | 2.8917 mL | 5.7835 mL | 14.4587 mL |
| 5 mM | 0.1157 mL | 0.5783 mL | 1.1567 mL | 2.8917 mL | |
| 10 mM | 0.0578 mL | 0.2892 mL | 0.5783 mL | 1.4459 mL | |
| 15 mM | 0.0386 mL | 0.1928 mL | 0.3856 mL | 0.9639 mL | |
| 20 mM | 0.0289 mL | 0.1446 mL | 0.2892 mL | 0.7229 mL | |
| 25 mM | 0.0231 mL | 0.1157 mL | 0.2313 mL | 0.5783 mL | |
| 30 mM | 0.0193 mL | 0.0964 mL | 0.1928 mL | 0.4820 mL | |
| 40 mM | 0.0145 mL | 0.0723 mL | 0.1446 mL | 0.3615 mL | |
| 50 mM | 0.0116 mL | 0.0578 mL | 0.1157 mL | 0.2892 mL |
DBCO-PEG3-Glu-Val-Cit-PABC-MMAE Related Classifications
HY-164309 Related Classifications
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