TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride
Based on 1 Customer Validation
TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride is a drug-linker conjugates for ADC>. TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride is the hydrochloride form of TLR7/8 agonist 4 hydroxy-PEG6-acid. TLR7/8 agonist 4 hydroxy-PEG6-acid consists of TLR7/8 agonist 4 (HY-139017) and a non-cleavable linker Hydroxy-PEG6-acid (HY-133050), and can be used for synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 95.54%
- Formula: C33H53ClN6O8
- Molecular Weight:697.26
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 697.26
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Formula C33H53ClN6O8
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Color White to off-white
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCN1CCN(CC1)C2=CC3=C(N=C(C4=C3NC(CCCC)=N4)N)C=C2)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (71.71 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.4342 mL | 7.1709 mL | 14.3419 mL | 35.8546 mL |
| 5 mM | 0.2868 mL | 1.4342 mL | 2.8684 mL | 7.1709 mL | |
| 10 mM | 0.1434 mL | 0.7171 mL | 1.4342 mL | 3.5855 mL | |
| 15 mM | 0.0956 mL | 0.4781 mL | 0.9561 mL | 2.3903 mL | |
| 20 mM | 0.0717 mL | 0.3585 mL | 0.7171 mL | 1.7927 mL | |
| 25 mM | 0.0574 mL | 0.2868 mL | 0.5737 mL | 1.4342 mL | |
| 30 mM | 0.0478 mL | 0.2390 mL | 0.4781 mL | 1.1952 mL | |
| 40 mM | 0.0359 mL | 0.1793 mL | 0.3585 mL | 0.8964 mL | |
| 50 mM | 0.0287 mL | 0.1434 mL | 0.2868 mL | 0.7171 mL | |
| 60 mM | 0.0239 mL | 0.1195 mL | 0.2390 mL | 0.5976 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
TLR7/8 agonist 4 hydroxy-PEG6-acid hydrochloride Related Classifications
HY-156691A Related Classifications
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