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Cat. No.: HY-130638

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(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

Name: (S,R,S)-AHPC-O-Ph-PEG1-NH-Boc
Brand: MedChemExpress
SKU: HY-130638
Availability: PreOrder

(Synonyms: VH032-O-Ph-PEG1-NH-Boc)

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3 ligase ligand-linker conjugate which is used for the EED-targeted PROTAC.

For research use only. We do not sell to patients.

CAS No.: 2409007-40-3
Formula: C₃₇H₄₉N₅O₈S
Molecular Weight:723.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc Chemical Structure

CAS No.: 2409007-40-3

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Description

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is a synthesized E3 ligase ligand-linker conjugate which is used for the EED-targeted PROTAC^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2409007-40-3
Molecular Weight 723.88
Formula C₃₇H₄₉N₅O₈S
SMILES

CC(C)([C@H](NC(COC1=CC=C(OCCNC(OC(C)(C)C)=O)C=C1)=O)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C=C3)C4=C(N=CS4)C)=O)=O)C
Synonyms

VH032-O-Ph-PEG1-NH-Boc
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc Related Classifications

HY-130638 Related Classifications

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