(S,R,S)-AHPC-PEG6-C4-NH2 hydrochloride
(S,R,S)-AHPC-PEG6-C4-NH2 hydrochloride is an E3 ligase ligand-linker conjugate containing a VHL ligand and linker based on (S,R,S)-AHPC. (S,R,S)-AHPC-PEG6-C4-NH2 hydrochloride can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- Formula: C40H66ClN5O10S
- Molecular Weight:844.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
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VHL |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 844.50
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Formula C40H66ClN5O10S
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SMILES
O=C(NCC1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(COCCOCCOCCOCCOCCOCCCCCCN)=O)C(C)(C)C)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)