BOC-NH-PEG2000-DMG
BOC-NH-PEG2000-DMG is a conjugate composed of a Boc-protected primary amine (-NH2), a PEG chain, and terminal dimyristoylglycerol (DMG). BOC-NH-PEG2000-DMG can be used for research in biomaterial construction and drug delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3083265-22-6
- 分子量:2000 (Average)
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
The structure of DMG-PEG-Galactose comprises three key components that work synergistically:
DMG: As a hydrophobic anchor, it is responsible for firmly embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
BOC-NH2: Boc is removed under acidic conditions, exposing the highly reactive primary amine (-NH2). The primary amine can chemically react with specific groups (such as carboxyl groups, activated esters, etc.) on the surface of drug molecules, proteins, antibodies, or nanoparticles, thereby achieving drug loading.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3083265-22-6
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分子量 2000 (Average)
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SMILES
CC(C)(C)OC(NCCOCCOCC(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)