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Art. -Nr.: HY-183127A

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BOC-NH-PEG2000-DMG

BOC-NH-PEG2000-DMG is a conjugate composed of a Boc-protected primary amine (-NH2), a PEG chain, and terminal dimyristoylglycerol (DMG). BOC-NH-PEG2000-DMG can be used for research in biomaterial construction and drug delivery.

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CAS. Nr.: 3083265-22-6
Molecular Weight:2000 (Average)

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

BOC-NH-PEG2000-DMG Chemical Structure

CAS. Nr.: 3083265-22-6

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Biologische Aktivität

Beschreibung

In Vitro

The structure of DMG-PEG-Galactose comprises three key components that work synergistically:
DMG: As a hydrophobic anchor, it is responsible for firmly embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: As a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
BOC-NH2: Boc is removed under acidic conditions, exposing the highly reactive primary amine (-NH2). The primary amine can chemically react with specific groups (such as carboxyl groups, activated esters, etc.) on the surface of drug molecules, proteins, antibodies, or nanoparticles, thereby achieving drug loading.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3083265-22-6
Molecular Weight 2000 (Average)
SMILES

CC(C)(C)OC(NCCOCCOCC(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.