Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
Based on 1 Customer Validation
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader. (From patent WO2017180417A1 compound s7).
For research use only. We do not sell to patients.
- Purity: 98.43%
- CAS No.: 1799711-31-1
- Formula: C30H42N4O11
- Molecular Weight:634.67
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
|
Cereblon |
Chemical Information
-
CAS No. 1799711-31-1
-
Appearance Solid
-
Molecular Weight 634.67
-
Formula C30H42N4O11
-
Color White to off-white
-
SMILES
O=C(NCCCOCCOCCOCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)OC(C)(C)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (157.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5756 mL | 7.8781 mL | 15.7562 mL | 39.3906 mL |
| 5 mM | 0.3151 mL | 1.5756 mL | 3.1512 mL | 7.8781 mL | |
| 10 mM | 0.1576 mL | 0.7878 mL | 1.5756 mL | 3.9391 mL | |
| 15 mM | 0.1050 mL | 0.5252 mL | 1.0504 mL | 2.6260 mL | |
| 20 mM | 0.0788 mL | 0.3939 mL | 0.7878 mL | 1.9695 mL | |
| 25 mM | 0.0630 mL | 0.3151 mL | 0.6302 mL | 1.5756 mL | |
| 30 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL | 1.3130 mL | |
| 40 mM | 0.0394 mL | 0.1970 mL | 0.3939 mL | 0.9848 mL | |
| 50 mM | 0.0315 mL | 0.1576 mL | 0.3151 mL | 0.7878 mL | |
| 60 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6565 mL | |
| 80 mM | 0.0197 mL | 0.0985 mL | 0.1970 mL | 0.4924 mL | |
| 100 mM | 0.0158 mL | 0.0788 mL | 0.1576 mL | 0.3939 mL |
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc Related Classifications
HY-145177 Related Classifications
Powered by Bioz