1799711-31-1
Chemical Structure
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc
- CAS No.: 1799711-31-1
- Formula:C30H42N4O11
- Molecular Weight:634.67
IUPAC Name: tert-butyl (1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)carbamate
InChIKey: GUERDSNOMPTZOW-UHFFFAOYSA-N
SMILES: O=C(NCCCOCCOCCOCCCNC(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O)OC(C)(C)C
Biological Activity: Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).
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Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc | 98.43% | Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader. (From patent WO2017180417A1 compound s7). | ||||||||||||||||||||
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