1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-PEG5-COOH

(S,R,S)-AHPC-PEG5-COOH (Synonyms: VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58)

Cat. No.: HY-130271
Handling Instructions

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology.

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(S,R,S)-AHPC-PEG5-COOH Chemical Structure

(S,R,S)-AHPC-PEG5-COOH Chemical Structure

CAS No. : 2172820-14-1

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Description

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].

IC50 & Target[1]

VHL

 

Molecular Weight

750.90

Formula

C₃₆H₅₄N₄O₁₁S

CAS No.

2172820-14-1

SMILES

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[[email protected]]3N(C([[email protected]](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)C[[email protected]](O)C3

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Please store the product under the recommended conditions in the Certificate of Analysis.

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(S,R,S)-AHPC-PEG5-COOH
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HY-130271
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